DRCR.net Protocol N
Posted by: Georgia Retina in
Research Title: An Evaluation of Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy Sponsor: The Diabetic Retinopathy Clinical Research Network Principal Investigator: Robert Stoltz, M.D Ph.D Description: To determine if intravitreal injections of ranibizumab decrease the proportion of eyes in which vitrectomy is performed compared with saline injections in eyes presenting with vitreous hemorrhage from proliferative diabetic…
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Gemini GEM-NH-002 Clarity 2
Posted by: Georgia Retina in
Research Title: A Prospective Natural History Study to Evaluate Clinical Characteristics and Disease Progression in Subjects with Non-Central Geographic Atrophy (GA) Who Are Carriers of High-Risk Genetic Variants of Complement Factor H (CFH) Sponsor: Gemini Therapeutics, Inc. Principal Investigator: Robert Stoltz, M.D., Ph.D. Description: This is a prospective, multicenter, natural history (NH) study, conducted in subjects with non-central GA…
Read More Genentech GR39821
Posted by: Georgia Retina in
Research Title: A Phase I, Multicenter, Open-Label, Single-Dose, Dose-Escalation, and Multiple-Dose Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of RO7171009 in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration. Sponsor: Genentech, Inc. Principal Investigator: Robert Stoltz, M.D., Ph.D. Description: This Phase 1, open-label, multicenter study will investigate the safety and tolerability of RO7171009 following…
Read More Graybug GBV-102-002 Altissimo
Posted by: Georgia Retina in
Research Title: A Phase 2b Multicenter Dose-Ranging Study Evaluating the Safety and Efficacy of Sunitinib Malate Depot Formulation (GB-102) Compared to Aflibercept in Subjects With Neovascular (Wet) Age-related Macular Degeneration (ALTISSIMO Study) Sponsor: Graybug Vision Principal Investigator: Atul Sharma, M.D. Description: Phase 2b, multicenter, visual examiner-masked, randomized active-controlled, parallel-arm design study to evaluate the safety and duration of the…
Read More HORIZON FVF3426g
Posted by: Georgia Retina in
Research Title: An Extension Study to Evaluate the Safety and Tolerability of Ranibizumab in Subjects With Choroidal Neovascularization Secondary to AMD or Macular Edema Secondary to RVO Sponsor: Genentech Principal Investigator: Jay Stallman, M.D. Description: This is an open-label, multicenter, extension study of intravitreally administered ranibizumab in subjects with primary or recurrent CNV secondary to AMD who have completed…
Read More AART C-02-60
Posted by: Georgia Retina in
Research Title: Anecortave Acetate Risk-Reduction Trial (AART) Sponsor: Allergan Principal Investigator: Atul Sharma, M.D. Description: A 48-month study of posterior juxtascleral administrations of Anecortave Acetate 15 or 30 mg or sham administration every 6 months. Start Date: March 2006 Recruitment: Completed Project Personnel: Leslie Marcus, CCRC Location(s): Riverdale; 155 Medical Way, Suite E, Riverdale, GA 30274
Read More Allergan 1771-201-008 MAPLE
Posted by: Georgia Retina in
Research Title: Evaluating Abicipar for Safety and Treatment Effect in Patients With Neovascular Age-related Macular Degeneration (AMD) Sponsor: Allergan Principal Investigator: Robert Stoltz, M.D., Ph.D. Description: The objective of this study is to evaluate abicipar for safety and treatment effect in patients with neovascular Age-related Macular Degeneration (AMD). Start Date: June 2018 Recruitment: Enrolling Project Personnel: Leslie Marcus, CCRC; Caitlin Harrison, CCRC,…
Read More ALLERGAN 206207-012
Posted by: Georgia Retina in
Research Title: Safety and Efficacy of a New Treatment in Combination With Laser for Diabetic Macular Edema Sponsor: Allergan Principal Investigator: Robert Stoltz, M.D., Ph.D Description: This study will evaluate the safety and efficacy of the intravitreal implant of dexamethasone with laser treatment vs. laser treatment alone in patients with diabetic macular edema. Start Date: April 2007 Recruitment: Completed Project Personnel: Leslie…
Read More AREDS2
Posted by: Georgia Retina in
Research Title: Age-Related Eye Disease Study 2 (AREDS2) Sponsor: National Eye Institute (NEI) Principal Investigator: Jay Stallman, M.D. Description: AREDS2 is a multi-center randomized trial of approximately 4,200 participants designed to assess the effects of oral supplementation of high doses of macular xanthophylls (lutein and zeaxanthin) and omega-3 LCPUFAs (DHA and EPA) for the treatment of AMD and cataract….
Read More Acucela 4429-202 SEATTLE
Posted by: Georgia Retina in
Research Title: A Phase 2b/3 Multicenter, Randomized, Double-Masked, Dose-Ranging Study Comparing the Efficacy and Safety of Emixustat Hydrochloride (ACU-4429) With Placebo for the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular Degeneration. Sponsor: Acucela Inc Principal Investigator: Mark J. Rivellese, M.D. Description: The purpose of this study is to determine if emixustat hydrochloride (ACU-4429) reduces the rate of…
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