Roche BP29647 AVENUE
Posted by: Georgia Retina in
Research Title: A Multiple-Center, Multiple-Dose and Regimen, Randomized, Active Comparator Controlled, Double-Masked, Parallel Group, 36 Week Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RG7716 Administered Intravitreally in Patients With Choroidal Neovascularization Secondary to Age-Related Macular Degeneration. Sponsor: Hoffmanm-La Roche Principal Investigator: Jay Stallman, M.D., F.A.C.S. Description: This study will evaluate the safety, tolerability, pharmacokinetics, and efficacy…
Read More
KalVista KVD011-201
Posted by: Georgia Retina in
Research Title: A randomized sham-controlled double-masked Phase 2a study of the efficacy, safety and tolerability of the intravitreal plasma kallikrein inhibitor, KVD001, in subjects with center-involving diabetic macular edema (ciDME) who have had prior anti-vascular endothelial growth factor (VEGF) treatment. Sponsor: KalVista Pharmaceticals, Ltd. Principal Investigator: Robert Stoltz, M.D., Ph.D Description: The purpose of this study is to evaluate…
Read More LFG316A2203
Posted by: Georgia Retina in
Research Title: A Multicenter, Randomized, Sham-control, Proof-of-concept Study of Intravitreal LFG316 in Patients With Geographic Atrophy Associated With Age-related Macular Degeneration Sponsor: Novartis Principal Investigator: Mark J. Rivellese, M.D. Description: This study is designed to test the efficacy of six successive monthly doses of intravitreal (IVT) LFG316 on the growth of geographic atrophy (GA) lesions. The study will also…
Read More OPH1004
Posted by: Georgia Retina in
Research Title: A Phase 3 Randomized, Double-Masked, Controlled Trial to Establish the Safety and Efficacy of Intravitreous Administration of Fovista® (Anti PDGF-B Pegylated Aptamer) Administered in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapy in Subjects With Subfoveal Neovascular Age-related Macular Degeneration. Sponsor: Ophthotech Corporation Principal Investigator: Atul Sharma, M.D. Description: Subjects will be randomized…
Read More MARINA FVF2598g
Posted by: Georgia Retina in
Research Title: A Study to Evaluate rhuFab V2 in Subjects With Minimally Classic or Occult Subfoveal Neovascular Macular Degeneration Sponsor: Genentech Principal Investigator: Jay Stallman, M.D. Description: The purpose of this study is to determine whether injections of rhuFab V2 into the eye can prevent vision loss in patients with age-related macular degeneration, and also to evaluate the safety…
Read More AREDS2
Posted by: Georgia Retina in
Research Title: Age-Related Eye Disease Study 2 (AREDS2) Sponsor: National Eye Institute (NEI) Principal Investigator: Jay Stallman, M.D. Description: AREDS2 is a multi-center randomized trial of approximately 4,200 participants designed to assess the effects of oral supplementation of high doses of macular xanthophylls (lutein and zeaxanthin) and omega-3 LCPUFAs (DHA and EPA) for the treatment of AMD and cataract….
Read More Acucela 4429-202 SEATTLE
Posted by: Georgia Retina in
Research Title: A Phase 2b/3 Multicenter, Randomized, Double-Masked, Dose-Ranging Study Comparing the Efficacy and Safety of Emixustat Hydrochloride (ACU-4429) With Placebo for the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular Degeneration. Sponsor: Acucela Inc Principal Investigator: Mark J. Rivellese, M.D. Description: The purpose of this study is to determine if emixustat hydrochloride (ACU-4429) reduces the rate of…
Read More Aerpio AKB-9778-CI-5001 TIME-2b
Posted by: Georgia Retina in
Research Title: Phase 2 Double-Masked, Placebo-Controlled Study to Assess the Safety and Efficacy of Subcutaneously Administered AKB-9778 15mg Once Daily or 15mg Twice Daily for 12 Months in Patients With Moderate to Severe Non-Proliferative Diabetic Retinopathy Sponsor: Aerpio Therapeutics, LLC Principal Investigator: Sri Krishna Mukkamala, M.D. Description: The purpose of this study is to evaluate the safety and efficacy…
Read More Allergan 150998-005 CEDAR
Posted by: Georgia Retina in
Research Title: A Safety and Efficacy Study of Abicipar Pegol in Patients With Neovascular Age-Related Macular Degeneration Sponsor: Allergan Principal Investigator: Robert A. Stoltz, M.D., Ph.D. Description: This is a safety and efficacy study of abicipar pegol in patients with neovascular age-related macular degeneration. Start Date: October 2015 Recruitment: Complete Project Personnel: Leslie Marcus, CCRC; Caitlin Harrison, CCRC, COA; Stephanie Campbell, CRC,…
Read More Allergan 190342-038 BEACON
Posted by: Georgia Retina in
Research Title: A Safety and Efficacy Study of Brimonidine Intravitreal Implant in Geographic Atrophy Secondary to Age-related Macular Degeneration. Sponsor: Allergan Principal Investigator: Mark J. Rivellese, M.D. Description: This study will assess the safety and efficacy of the brimonidine intravitreal implant in patients with geographic atrophy due to age-related macular degeneration. Start Date: December 2015 Recruitment: Completed Project Personnel: Leslie Marcus, CCRC;…
Read More 
