Research Title: A Multicenter, Randomized, Sham-control, Proof-of-concept Study of Intravitreal LFG316 in Patients With Geographic Atrophy Associated With Age-related Macular Degeneration

Sponsor: Novartis

Principal Investigator: Mark J. Rivellese, M.D.

Description: This study is designed to test the efficacy of six successive monthly doses of intravitreal (IVT) LFG316 on the growth of geographic atrophy (GA) lesions. The study will also provide information on the safety, tolerability, serum concentrations and pharmacodynamics of multiple intravitreal (IVT) doses of LFG316.

Start Date: March 2012

Recruitment: Completed

Project Personnel: Leslie Marcus, CCRC

Location(s): Tucker; 1462 Montreal Road West, Suite 412, Tucker, GA 30084